C E M = ∫ t o t file R T r e f e r e n c e − T d t displaystyle mathit CEM =int _ t_ o ^ t_ f R^ T_ mathrm reference -T dt l. Suited to persons in excess of 30, the skin just began to enter the getting older, only one therapy may help accelerate the active cells, the treatment method outcome is more major and extensive-Long last